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Abstract Detail



Recent Topics Posters

Adongbede , Erute Magdalene [1], Sholola, Motunrayo Titi [2].

Antimicrobial properties of Daedaleaquercina and Polyporusversicolor from South-West Nigeria.

The need for new antimicrobials in the developing countries has become very apparent because of abundance of fake drugs and rising cost of antibiotics. The polypores Daedalea quercina and Polyporus versicolor collected from the wild in Lagos, Southwest Nigeria were investigated for antimicrobial activities. The paper disc diffusion method was used for this investigation. Chemical analyses of the polypore were also carried out to check for bioactive compounds. Extraction of active compounds from the polypore was done using three solvents - chloroform, methanol and ethanol. The chemical analyses of these polypores indicated the presence of tannins, flavonoids, saponins and terpenoids in varying concentrations. Phlobatannins were not present in Daedalea quercina but present in Polyporus versicolor.  The type of solvent used affected the concentration of the various compounds extracted from the tissues of the polypores and also their antimicrobial effects. Chloroform extracts of Daedalea quercina inhibited all the pathogens tested (Aspergilus fumigatus, A. flavus, A. niger, A. ochraceus, Candida albicans, Penicillium italicum, Escherichia coli, Staphylococcus aureus and Streptococcus faecalis) while that of Polyporus versicolor did not all. The ethanol and methanol extracts of D. quercina did not inhibit the growth of all the pathogens. The ethanol extract of D. quercina had no effect on Streptococcus faecalis but that of Polyporus versicolor caused total inhibition of same pathogen. The methanol extract of D. quercina also had no effect on Aspergilus fumigatus but that of Polyporus versicolor showed total inhibition. Seven pathogens were totally inhibited by the extracts of Polyporus versicolor while three were totally inhibited by D. quercina. The extracts that were active showed higher zones of inhibition than the standard antibiotics used for the treatment of infections caused by these pathogens. More work still has to be done to identify and extract the active components with the aim of getting new antimicrobials.

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1 - University of Lagos, Botany, University Road, Akoka, Yaba, Lagos, Lagos, 01234, Nigeria
2 -

Keywords:
Polypore
antifungal
antibacterial
Paper disc diffusion
Extracts.

Presentation Type: Recent Topics Poster
Session: P
Location: Grand Salon A - D/Riverside Hilton
Date: Monday, July 29th, 2013
Time: 5:30 PM
Number: PRT020
Abstract ID:1311
Candidate for Awards:None


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